By G. Gamal. University of Wisconsin-Whitewater. 2018.
Specific Measures Allergic Asthma Specific allergy management must be included in the treatment regimen of allergic asthma cheap ayurslim 60 caps with amex. Most allergic patients purchase ayurslim 60 caps without a prescription, however, are sensitive to more than one allergen, and many allergens cannot be removed completely. Foods are almost never the cause of asthma, except occasionally in children and infants, but they often are incriminated erroneously. Patients may attribute their respiratory symptoms to aspartame or monosodium glutamate when such associations are not justified. Exposure to sulfur dioxide from sodium or potassium metabisulfite used as an antioxidant in foods can cause acute respiratory symptoms in patients with asthma. However, patients with stable asthma who are managed by antiinflammatory medications will not be affected significantly by metabisulfite. Dacron (or hypoallergenic) pillows are preferred and should be enclosed in zippered encasings. In some situations, additional cleaning or removal of rugs (especially old ones) is beneficial. Other aspects may be considered with regard to the environmental control in the home. Basement apartments, because of increased moisture, are most likely to have higher levels of airborne fungi and mite antigens. For the highly dust-allergic patient, appropriate furnace filters and precipitators should be used and maintained properly. When environmental control is either impossible or insufficient to control symptoms, allergen immunotherapy should be included as a form of immunomodulation. Efficacy in asthma has been documented for pollens, dust mite, and Cladosporium species (171,208). Other than very modest effects, immunotherapy with cat dander extracts has not been impressive in reducing symptoms when the cat remains in the home environment. Johnstone and Dutton (263), in a 14-year prospective study of allergen immunotherapy for asthmatic children, have shown that 72% of the treated group were free of symptoms at 16 years of age, as compared with only 22% of the placebo group. Similar data have been generated again in that rhinitis patients who received allergen immunotherapy had less emergence of asthma than rhinitis patients who did not receive allergen immunotherapy ( 264). Nonallergic Asthma Treatment of nonallergic asthma primarily involves the judicious use of pharmacologic therapy. Convincing evidence is available that virus-induced upper respiratory infections initiate exacerbations of asthma. Annual influenza vaccination should be administered according to the Centers for Disease Control and Prevention recommendations for children and adults. Pneumococcal vaccine can be administered to patients with persistent asthma, although pneumococcal pneumonia is an infrequent occurrence. Aspirin-sensitive Asthma Treatment of aspirin-sensitive asthma is similar to that of nonallergic asthma, except for those patients in whom there is clinical and skin test evidence of contributing inhalant allergy. Patients must be informed that numerous proprietary mixtures contain aspirin, and they must be certain to take no proprietary medication that contains acetylsalicylic acid. Other patients respond with urticaria, angioedema, or a severe reaction resembling anaphylaxis. Some physicians include both groups of patients as aspirin reactors, but others consider that the group in whom aspirin causes asthma differs from the group in whom urticaria, angioedema, or the anaphylactic type of reaction occurs. Reduced risk appears to be the case with the cyclooxygenase-2 inhibitors ( 187,188). The relationship that this intolerance bears to rhinitis, nasal polyposis, and asthma is unclear. The physician should be in attendance at all times because of the explosiveness and severity of these reactions. Aspirin should be administered in serial doubling doses, beginning with 3 or 30 mg ( 12,265). The physician should be experienced in this type of challenge, and the patient should be fully informed about potential risks and benefits. Serial test dosing with aspirin in patients with aspirin-sensitive asthma has been reported as a possible specific therapeutic modality. Patients then were treated for 3 months with aspirin and, as a group, experienced fewer nasal symptoms, but unfortunately only half of patients had a reduction in asthma symptoms ( 267). The use of prednisone and other antiasthmatic medications was not different after aspirin desensitization. Thus, although it is possible to administer aspirin cautiously to patients with proven bronchospastic responses to aspirin, the subsequent administration of aspirin for a 3-month period did not alter the severity of asthma, with only a few exceptions.
Obstructive sleep apnea syndrome and tracheostomy: long term follow up experience buy cheap ayurslim 60caps line. The efficacy of surgical modification of the upper airway in adults with obstructive sleep apnea syndrome buy generic ayurslim 60 caps on-line. Impaired central chemoreceptor function and chronic hypoventilation many years following poliomyelitis. Primary alveolar hypoventilation treated with nocturnal electrophrenic respiration. Prevalence of narcolepsy symptomatology and diagnosis in the European general population. The epidemiology of narcolepsy in Olmsted County, Minnesota a population based study. When cough lingers, however, it becomes a troubling problem for the patient and may indicate a more serious underlying condition that requires medical attention. The importance of cough as a clinical problem is reflected in the fact that recently, three major organizations of pulmonary physicians have published guidelines on the management of cough. If a cough persists for greater than three but less than eight weeks, it is termed subacute. Chronic cough refers to a cough that has been present for greater than eight weeks. Classifcation of Cough by Duration Acute < 3 Weeks Subacute 3 - 8 Weeks Chronic > 8 Weeks Table 2-12. An intact cough reflex effectively clears secretions out of the lungs, and prevents foreign objects from entering the airways. The nature of the communication between the receptors in the respiratory tract and the brain remains poorly understood. It is typically non-productive (dry) or is accompanied by small amounts of clear phlegm. Unfortunately, there is very little scientific evidence that many of the commonly-used cough and cold products sold worldwide are actually effective against cough due to the common cold. One potential drawback of the so-called older-generation antihistamines is that they may cause sedation (drowsiness). However, it is important to understand that the sudden onset of cough can represent a serious underlying condition that requires immediate medical attention. If these symptoms were associated with high fever, chest pain on breathing in, or significant illness, pneumonia would need to be excluded. The production of pink, frothy sputum in the setting of shortness of breath and/ or chest pain could indicate pulmonary edema (lungs filling up with fluid) that is a sign of heart failure. There are several likely explanations for the guidelines conclusion, which was based on a thorough review of the medical literature. Firstly, the guidelines evaluated only studies that were performed in a scientifically rigorous manner. Secondly, studies of potential therapies for acute cough are difficult to perform. Since acute cough due to the common cold typically resolves spontaneously within a few days, it is challenging to design a study that could demonstrate a drug to be more effective than a placebo. For statistical reasons, a very large number of subjects would need to be evaluated, thus necessitating lengthy and expensive trials. Further complicating matters is the fact that there has been a strong placebo response noted in cough trials. For example, dextromethorphan is a non-narcotic opioid drug that is a component of hundreds of cough and cold preparations sold worldwide. Studies have shown that dextromethorphan, at doses of 30 mg or more, is an effective cough suppressant. Why this so-called postviral (or postinfectious) cough lingers in a subgroup of individuals is not well understood. It is probably due to severe irritation of the cough receptors by the initial viral infection of the airways, and subsequent inability of the inflamed area to heal because of persistent coughing that continues to irritate the lining of the respiratory tract. For severe cough, a 1-2 week course of oral steroid therapy (with prednisone, for example) is often effective. This rise in the incidence of whooping cough is likely due to the waning of immunity that was acquired by adults who had infection prior to the availability of the pertussis vaccine in the 1950s, and, the waning of immunity provided by vaccines that were administered more than a decade previously. Some cases of subacute cough will persist beyond eight weeks and therefore will fulfill the definition of chronic cough. Chronic cough is a serious issue not only because it exposes an underlying illness, but also because of its effect on an individual s quality of life. Many patients who have suffered from chronic cough for months or years become socially isolated, afraid to go out in public for fear of a severe coughing attack drawing unwanted attention. Further worsening the situation is the effect that an individual s chronic cough can have on spouses, family members and coworkers. It is not surprising, therefore, that a recent study demonstrated a very high incidence of symptoms of depression among patients presenting to a specialized cough center for evaluation and treatment. Cough may result from the inciting inflammatory process stimulating cough receptors in the upper airway, or from mucus dripping down into the back of the throat and mechanically inducing cough.
Prevalence of cocaine use and its impact on asthma exacerbation in an urban population buy ayurslim 60 caps with mastercard. Rapid-onset asthma attack: a prospective cohort study about characteristics and response to emergency department treatment 60 caps ayurslim otc. Mechanisms of hypoxemia in patients with status asthmaticus requiring mechanical ventilation. Arterial blood gases and pulmonary function testing in acute bronchial asthma: predicting patient outcomes. Airway obstruction and ventilation perfusion relationships in acute severe asthma. Serial relationships between ventilation perfusion inequality and spirometry in acute severe asthma requiring hospitalization. Assessment of the patient with acute asthma in the emergency department: a factor analytic study. The application of an asthma severity index in patients with potentially fatal asthma. A cohort analysis of excess mortality in asthma and the use of inhaled beta-agonists. Cardiac dysrhythmias during the treatment of acute asthma: a comparison of two treatment regimens by a double blind protocol. The effects of deep inhalation on maximal expiratory flow during intensive treatment of spontaneous asthmatic episodes. Cardiorespiratory arrest following peak expiratory flow measurement during attack of asthma. Emergency room treatment of asthma: relationships among therapeutic combinations, severity of obstruction and time course of response. Early prediction of poor response in acute asthma patients in the emergency department. Failure of peak expiratory flow rate to predict hospital admission in acute asthma. Continuous intravenous terbutaline infusions for adult patients with status asthmaticus. Routine chest radiographs in exacerbations of acute obstructive pulmonary disease. A pilot study of steroid therapy after emergency department treatment of acute asthma: is a taper needed? Comparison of intramuscular triamcinolone and oral prednisone in the outpatient treatment of acute asthma: a randomized controlled trial. Ventilation perfusion mismatching in acute severe asthma: effects of salbutamol and 100% oxygen. Continuous versus intermittent nebulization of salbutamol in acute severe asthma: a randomized, controlled trial. Effect of outpatient treatment of asthma with beta agonists on the response to sympathomimetics in an emergency room. Comparison of intermittent and continuously nebulized albuterol for treatment of asthma in an urban emergency department. Continuous versus intermittent albuterol nebulization in the treatment of acute asthma. Beta-adrenoceptor responses to high doses of inhaled salbutamol in patients with bronchial asthma. Cardiovascular safety of high doses of inhaled fenoterol and albuterol in acute severe asthma. Isoetharine versus albuterol for acute asthma: greater immediate effect, but more side effects. Improved bronchodilation with levalbuterol compared with racemic albuterol in patients with asthma. A randomized, placebo-controlled study to evaluate the role of salmeterol in the in-hospital management of asthma. Emergency department treatment of severe asthma: metered-dose inhaler plus holding chamber is equivalent in effectiveness to nebulizer. A comparison of albuterol administered by metered dose inhaler (and holding chamber) or wet nebulizer in acute asthma. Efficacy of albuterol administered by nebulizer versus spacer device in children with acute asthma. Treatment of acute asthma: is combination therapy with sympathomimetics and methylxanthines indicated? Comparison of nebulized terbutaline and subcutaneous epinephrine in the treatment of acute asthma. Inhaled salbutamol (albuterol) vs injected epinephrine in the treatment of acute asthma in children. Epinephrine improves expiratory airflow rates in patients with asthma who do not respond to inhaled metaproterenol sulfate.
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